1) If you don't have time to do a thorough cleaning, focus on the main areas where guests will be (like livingroom, diningroom, kitchen and bathrooms).
2) Focus on floors--they make the most impression.
3) Use a designated room like an office to toss the clutter if you don't have time to deal with it.
4) Use scents, like essential oil sticks, to give your home a festive, homey feel.
Happy holidays!